Drug shortages have been troubling the oncology community for more than 2 years. But in a study published in The New England Journal of Medicine in late 2012, we received the first proof that drug substitution can most definitely lead to...
Pain is a symptom associated with prolonged recovery from illness and procedures, decreased quality of life, and increased health-care costs. While there have been advances in the management of cancer pain, there is a need for therapeuti...
Palifermin is a recombinant human keratinocyte growth factor that stimulates proliferation and differentiation of epithelial cells. Palifermin’s biological activity exerts cytoprotective and healing effects that decrease cell injury caus...
Tumor lysis syndrome (TLS), an oncologic emergency that typically occurs after the treatment of a malignancy with chemotherapy and/or radiotherapy, is the result of extreme tumor cell lysis with the release of intracellular potassium, nu...
As Americans age, health-care providers will be faced with new and challenging issues related to the care of older adults. One critical issue unique to the aging population is polypharmacy. Cancer-related medications can add to the compl...
Case Study
Amy is a 44-year-old woman with severe autism. She lives with her sister Susan, who is her caregiver and guardian. Amy is ambulatory and able to dress and feed herself. She is a healthy individual with no other significant co...
In late 2012, regorafenib (Stivarga), a novel oral multikinase inhibitor, was approved by the FDA for certain previously treated patients with metastatic colorectal cancer. Even more recently, regorafenib received another approval for us...
We all know that through television and the Internet, our patients are exposed to a staggering amount of information on complementary and alternative treatments. Some of these treatments are legitimate and potentially helpful, but some c...